Rabbit Secondary Antibodies
ABclonal Technology 488 Rabbit anti-Human PTH1R
The protein encoded by this gene is a member of the G-protein coupled receptor family 2 This protein is a receptor for parathyroid hormone (PTH) and for parathyroid hormone-like hormone (PTHLH) The activity of this receptor is mediated by G proteins which activate adenylyl cyclase and also a phosphatidylinositol-calcium second messenger system Defects in this receptor are known to be the cause of Jansen s metaphyseal chondrodysplasia (JMC) chondrodysplasia Blomstrand type (BOCD) as well as enchodromatosis Two transcript variants encoding the same protein have been found for this gene
ABclonal Technology 594 Rabbit anti-Human CD177
This gene encodes a glycosyl-phosphatidylinositol (GPI)-linked cell surface glycoprotein that plays a role in neutrophil activation The protein can bind platelet endothelial cell adhesion molecule-1 and function in neutrophil transmigration Mutations in this gene are associated with myeloproliferative diseases Over-expression of this gene has been found in patients with polycythemia rubra vera Autoantibodies against the protein may result in pulmonary transfusion reactions and it may be involved in Wegener s granulomatosis A related pseudogene which is adjacent to this gene on chromosome 19 has been identified
Abcam Rabbit Anti-Human IgG H&L (Alkaline Phosphatase)
Rabbit Anti-Human IgG H&L (Alkaline Phosphatase)
The product is subject to the following: Abcam Restricted Use Statement
Vector Laboratories RABBIT ANTI HUMAN MFSD2A
Polyclonal Rabbit anti Human MFSD2A Antibody (FITC, N Terminus, WB)
ABclonal Technology 647 Rabbit anti-Human CD177
This gene encodes a glycosyl-phosphatidylinositol (GPI)-linked cell surface glycoprotein that plays a role in neutrophil activation The protein can bind platelet endothelial cell adhesion molecule-1 and function in neutrophil transmigration Mutations in this gene are associated with myeloproliferative diseases Over-expression of this gene has been found in patients with polycythemia rubra vera Autoantibodies against the protein may result in pulmonary transfusion reactions and it may be involved in Wegener s granulomatosis A related pseudogene which is adjacent to this gene on chromosome 19 has been identified
ABclonal Technology PE Rabbit anti-Human CD72 mAb
Predicted to enable signaling receptor binding activity Predicted to be involved in cell adhesion Is integral component of plasma membrane
ABclonal Technology PE Rabbit anti-Human CD72 mAb
Predicted to enable signaling receptor binding activity Predicted to be involved in cell adhesion Is integral component of plasma membrane
ABclonal Technology 488 Rabbit anti-Human CD71
This gene encodes a cell surface receptor necessary for cellular iron uptake by the process of receptor-mediated endocytosis This receptor is required for erythropoiesis and neurologic development Multiple alternatively spliced variants have been identified
ABclonal Technology 594 Rabbit anti-Human DLL4
This gene is a homolog of the Drosophila delta gene The delta gene family encodes Notch ligands that are characterized by a DSL domain EGF repeats and a transmembrane domain
ABclonal Technology 488 Rabbit anti-Human DLL4
This gene is a homolog of the Drosophila delta gene The delta gene family encodes Notch ligands that are characterized by a DSL domain EGF repeats and a transmembrane domain
ABclonal Technology 594 Rabbit anti-Human CD72
Predicted to enable signaling receptor binding activity Predicted to be involved in cell adhesion Is integral component of plasma membrane
STEMCELL Technologies Human Recombinant Fractalkine (CX3CL1), Size: 1000 µg
Mediate cell migration and adhesion with fractalkine (White & Greaves. Arterioscler Thromb Vasc Biol, 2012). Fractalkine (CX3CL1) is characterized by a C-X3-C cysteine motif within the chemokine domain (Bazan et al. Nature, 1997). The chemokine domain is connected to a mucin-like stalk, followed by a transmembrane region and a C-terminal intracellular domain (Jones et al. Mol Interv, 2010). Cleavage at the base of the stalk generates a soluble chemokine, which acts as a chemoattractant of target cells (Apostolakis & Spandidos. Acta Pharmacol Sin, 2013). The protein signals through interaction with CX3CR1, which is expressed on monocytes, NK cells, T cells, microglia, and smooth muscle cells. Human recombinant fractalkine from STEMCELL comes lyophilized with ≥ 95% purity; EC50 ≤ 1.5 μg/mL; endotoxin levels verified ≤ 0.2 EU/μg protein. Alternative names: C3Xkine, Chemokine (C-X3-C motif) ligand 1, FKN, Neurotactin, NTN, NTT, SCYD1, Small inducible cytokine subfamily D member 1.
ABclonal Technology 647 Rabbit anti-Human TREM1
This gene encodes a receptor belonging to the Ig superfamily that is expressed on myeloid cells This protein amplifies neutrophil and monocyte-mediated inflammatory responses triggered by bacterial and fungal infections by stimulating release of pro-inflammatory chemokines and cytokines as well as increased surface expression of cell activation markers Alternatively spliced transcript variants encoding different isoforms have been noted for this gene
ABclonal Technology PE Rabbit anti-Human CD146 mAb
Melanoma cell adhesion molecule (MCAM MUC18 CD146) is an immunoglobulin superfamily member that acts as a cell surface adhesion protein and a marker of melanoma progression and metastasis It is expressed in vascular endothelial cells activated T lymphocytes smooth muscle and bone marrow stromal cells MCAM expression increases in endothelial cells in angiogenesis-related disorders including inflammatory bowel disease Crohn s disease rheumatoid arthritis tumors and chronic renal failure In the hematopoietic microenvironment MCAM-expressing human mesenchymal stromal cells (hMSC) maintain hematopoietic stem and progenitor cell (HSPC) self-renewal MCAM also plays a role in multiple sclerosis facilitating lymphocyte transmigration across the blood-brain barrier leading to inflammatory lesions in the central nervous system
ABclonal Technology PE Rabbit anti-Human MICA/MICB
This gene encodes a heavily glycosylated protein which is a ligand for the NKG2D type II receptor Binding of the ligand activates the cytolytic response of natural killer (NK) cells CD8 alphabeta T cells and gammadelta T cells which express the receptor This protein is stress-induced and is similar to MHC class I molecules however it does not associate with beta-2-microglobulin or bind peptides Alternative splicing results in multiple transcript variants